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Human liquor means waste content from bowels isolated to investigate specific enzymes and peptidases involved in enteric contraction and digestion of compounds.
P-endopeptidase isolated from human liquor inactivates tachykinins. Hydrolysis of Substance P by P-endopeptidase yields the active fragment of substance P. A neuroactive peptide, Substance P is found throughout the central and peripheral nervous system. It has mostly been studied for its contractive effect on enteric musculature.
References
- Nyberg et al. 1984
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