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What are hydrochlorothiazide; lisinopril tablets?

HYDROCHLOROTHIAZIDE; LISINOPRIL (Prinzide® or Zesteretic®) is a combination of two drugs used to lower blood pressure. Lisinopril is an ACE inhibitor that controls high blood pressure (hypertension) by relaxing blood vessels. Hydrochlorothiazide is a diuretic. High blood pressure can damage the blood vessels of the brain, heart, and kidneys, resulting in a stroke, heart failure, or kidney failure. By lowering blood pressure, hydrochlorothiazide; lisinopril can help reduce your risk of having damage to your kidneys, heart, or other organs. This medicine does not cure high blood pressure. Generic hydrochlorothiazide; lisinopril tablets are available.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:
• autoimmune disease (e.g., lupus), or suppressed immune function
• previous swelling of the tongue, face, or lips with difficulty breathing, difficulty swallowing, hoarseness, or tightening of the throat (angioedema)
• bone marrow disease
• diabetes mellitus
• gout
• heart or blood vessel disease
• liver disease
• recent heart attack or stroke
• kidney disease, (e.g. renal failure or renal artery stenosis)
• pancreatitis
• electrolyte imbalance (e.g. low or high levels of potassium in the blood)
• if you are on a special diet, such as a low-salt diet (e.g. using potassium substitutes)
• sulfonamide (sulfa) or thiazide allergy
• an unusual or allergic reaction to lisinopril, hydrochlorothiazide, other medicines, foods, dyes, or preservatives
• pregnant or trying to get pregnant
• breast-feeding

How should I use this medicine?

Take hydrochlorothiazide; lisinopril tablets by mouth. Follow the directions on the prescription label. You may take hydrochlorothiazide; lisinopril with or without food. Swallow the tablets with a drink of water. Take your doses at regular intervals. Do not take your medicine more often than directed. Do not stop taking this medicine except on your prescriber's advice.

Many patients with high blood pressure will not notice any signs of the problem. Therefore, it is very important that you take this medicine exactly as directed and that you keep your appointments with your prescriber or health care professional even if you feel well.

Contact your pediatrician or health care professional regarding the use of this medicine in children. Special care may be needed.

What if I miss a dose?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

What drug(s) may interact with hydrochlorothiazide; lisinopril?

• antiinflammatory drugs (NSAIDs, such as ibuprofen)
• calcium supplements
• cholestyramine
• colestipol
• dofetilide
• gold compounds, often used for arthritis
• hawthorn
• lithium
• medicines for diabetes
• medicines for high blood pressure
• monoamine oxidase inhibitors (Azilect®, Eldepryl®, Emsam®, Marplan®, Nardil®, Parnate®, Zelapar™)
• potassium salts or potassium supplements
• potassium-sparing diuretics (e.g., amiloride, triamterene)

Tell your prescriber or health care professional about all other medicines you are taking, including nonprescription medicines, nutritional supplements, or herbal products. Also tell your prescriber or health care professional if you are a frequent user of drinks with caffeine or alcohol, if you smoke, or if you use illegal drugs. These may affect the way your medicine works. Check with your health care professional before stopping or starting any of your medicines.

What should I watch for while taking hydrochlorothiazide; lisinopril?

Check your blood pressure regularly while you are taking hydrochlorothiazide; lisinopril. Ask your prescriber or health care professional what your blood pressure should be and when you should contact him or her. When you check your blood pressure, write down the measurements to show your prescriber or health care professional. You must not get dehydrated, ask your prescriber or health care professional how much fluid you need to drink a day. If you are taking this medicine for a long time you must visit your prescriber or health care professional for regular checks on your progress. Make sure you schedule appointments on a regular basis.

Check with your prescriber or health care professional if you get an attack of severe diarrhea, nausea and vomiting, or if you sweat a lot. The loss of too much body fluid can make it dangerous for you to take hydrochlorothiazide; lisinopril.

You may get dizzy. Do not drive, use machinery, or do anything that requires mental alertness until you know how hydrochlorothiazide; lisinopril affects you. To avoid dizzy or fainting spells, do not stand or sit up quickly. Alcohol may increase the possibility of dizziness. Avoid alcoholic drinks until you have discussed their use with your prescriber or health care professional.

If you are going to have surgery, tell your prescriber or health care professional that you are taking hydrochlorothiazide; lisinopril.

Avoid salt substitutes unless you are told otherwise by your prescriber or health care professional.

Do not take medicines for appetite control, asthma, colds, cough, hay fever, or sinus problems without asking your prescriber or health care professional for advice. Do not treat yourself for a fever or sore throat; check with your prescriber or health care professional first.

Hydrochlorothiazide; lisinopril may affect your blood sugar level. If you have diabetes, check with your prescriber or health care professional before changing the dose of your diabetic medicine.

Women should inform their doctor if they wish to become pregnant or think they might be pregnant. There is a potential for serious side effects to an unborn child. Talk to your health care professional or pharmacist for more information.

What side effects may I notice from taking hydrochlorothiazide; lisinopril?

Side effects that you should report to your prescriber or health care professional as soon as possible:
Rare or uncommon:
• difficulty breathing, difficulty swallowing, hoarseness, or tightening of the throat
• redness, blistering, peeling or loosening of the skin, including inside the mouth
• swelling of your face, lips, tongue, hands, or feet
• unusual rash, bleeding or bruising, or pinpoint red spots on the skin
Other:
• confusion, dizziness, lightheadedness or fainting spells
• decreased amount of urine passed
• decreased sexual function
• fast or uneven heart beat, palpitations, or chest pain
• fever or chills
• irregular heartbeat
• muscle cramps
• stomach pain
• vomiting
• unusual tiredness or weakness
• worsened gout pain
• yellowing of the eyes or skin

Side effects that usually do not require medical attention (report to your prescriber or health care professional if they continue or are bothersome):
• cough
• diarrhea
• headache
• increased sensitivity to the sun
• nausea
• tiredness or fatigue

Where can I keep my medicine?

Keep out of the reach of children.

Store at room temperature below 15—30 degrees C (59—86 degrees F). Protect from moisture and excessive light. Keep container tightly closed. Throw away any unused medicine after the expiration date.

Important Disclaimer: The drug information provided here is for educational purposes only. It is intended to supplement, not substitute for, the diagnosis, treatment and advice of a medical professional. This drug information does not cover all possible uses, precautions, side effects and interactions. It should not be construed to indicate that this or any drug is safe for you. Consult your medical professional for guidance before using any prescription or over the counter drugs.