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Immunoglobulin allotype

 
Wikipedia: Immunoglobulin allotype
The allotype affects the constant region (labeled CL and CH1-3 in the diagram.)

In immunology, an immunoglobulin allotype is the allele of the antibody chains found in the individual.

To reduce risk of transplant rejection, tissue typing is used to try to match donors and recipients with the same or similar allotypes.

The most important types are Gm (heavy chain) and km (light chain).

It can be used in resolving paternity disputes.[1]

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Wikipedia. This article is licensed under the Creative Commons Attribution/Share-Alike License. It uses material from the Wikipedia article "Immunoglobulin allotype" Read more