The Independent Spirit Award for Best Lead Female is given in recognition of achievements by actresses in leading roles in independent films.
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Winners and Nominees
1980s
- 1985: Geraldine Page - The Trip to Bountiful
- 1986: Isabella Rossellini - Blue Velvet
- 1987: Sally Kirkland - Anna
- Lillian Gish - The Whales of August
- Debra Sandlund - Tough Guys Don't Dance
- Louise Smith - Working Girls
- Joanne Woodward - The Glass Menagerie
- 1988: Jodie Foster - Five Corners
- Ricki Lake - Hairspray
- Nobu McCarthy - The Wash
- Julia Roberts - Mystic Pizza
- Meg Ryan - Promised Land
1990s
- 1990: Anjelica Huston - The Grifters
- Mary Alice - To Sleep with Anger
- Eszter Balint - Bail Jumper
- Carolyn Farina - Metropolitan
- Joanne Woodward - Mr. & Mrs. Bridge
- 1991: Judy Davis - Impromptu
- Patsy Kensit - Twenty-One
- Mimi Rogers - The Rapture
- Lili Taylor - Bright Angel
- Lily Tomlin - The Search for Signs of Intelligent Life in the Universe
- 1992: Fairuza Balk - Gas Food Lodging
- 1993: Ashley Judd - Ruby in Paradise
- 1994: Linda Fiorentino - The Last Seduction
- 1995: Elisabeth Shue - Leaving Las Vegas
- 1996: Frances McDormand - Fargo
- 1997: Julie Christie - Afterglow
- 1998: Ally Sheedy - High Art
- Katrin Cartlidge - Claire Dolan
- Christina Ricci - The Opposite of Sex
- Robin Tunney - Niagara, Niagara
- Alfre Woodard - Down in the Delta
- 1999: Hilary Swank - Boys Don't Cry
- Diane Lane - A Walk on the Moon
- Janet McTeer - Tumbleweeds
- Susan Traylor - Valerie Flake
- Reese Witherspoon - Election
2000s
- 2000: Ellen Burstyn - Requiem for a Dream
- 2001: Sissy Spacek - In the Bedroom
- 2002: Julianne Moore - Far from Heaven
- 2003: Charlize Theron - Monster
- 2004: Catalina Sandino Moreno - Maria Full of Grace
- Kimberly Elise - Woman Thou Art Loosed
- Vera Farmiga - Down to the Bone
- Judy Marte - On the Outs
- Kyra Sedgwick - Cavedweller
- 2005: Felicity Huffman - Transamerica
- 2006: Shareeka Epps - Half Nelson
- 2007: Ellen Page - Juno
- 2008: Melissa Leo - Frozen River
- Summer Bishil - Towelhead
- Anne Hathaway - Rachel Getting Married
- Tarra Riggs - Ballast
- Michelle Williams - Wendy and Lucy
- 2009: TBA
- Maria Bello - Downloading Nancy
- Nisreen Faour - Amreeka
- Helen Mirren - The Last Station
- Gwyneth Paltrow - Two Lovers
- Gabourey Sidibe - Precious
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