Interleukin-12 receptor

interleukin 12 receptor, beta 1
Identifiers
Symbol	IL12RB1
Alt. Symbols	IL12RB, CD212
Entrez	3594
HUGO	5971
OMIM	601604
RefSeq	NM_005535
UniProt	P42701
Other data
Locus	Chr. 19 p13.1

beta 2 subunit, interleukin 12 receptor, beta 2
Identifiers
Symbol	IL12RB2
Entrez	3595
HUGO	5972
OMIM	601642
RefSeq	NM_001559
UniProt	Q99665
Other data
Locus	Chr. 1 p31.3-31.2

Interleukin 12 receptor is a type I cytokine receptor, binding interleukin 12. It consists of beta 1^[1] and beta 2 subunits.^[2]

References

1. ^ Chua AO, Chizzonite R, Desai BB, Truitt TP, Nunes P, Minetti LJ, Warrier RR, Presky DH, Levine JF, Gately MK (1994). "Expression cloning of a human IL-12 receptor component. A new member of the cytokine receptor superfamily with strong homology to gp130". J. Immunol. 153 (1): 128–36. PMID 7911493. http://www.jimmunol.org/cgi/content/abstract/153/1/128. 
2. ^ Presky DH, Yang H, Minetti LJ, Chua AO, Nabavi N, Wu CY, Gately MK, Gubler U (1996). "A functional interleukin 12 receptor complex is composed of two beta-type cytokine receptor subunits". Proc. Natl. Acad. Sci. U.S.A. 93 (24): 14002–7. doi:10.1073/pnas.93.24.14002. PMID 8943050. 

External links

• MeSH Receptors,+Interleukin-12

This membrane protein-related article is a stub. You can help Wikipedia by expanding it.

v • d • e Transmembrane receptors: immune receptors Cytokine receptor Type I Interleukins (2, 3, 4, 5, 6, 7, 9, 11, 12, 13, 15, 21, 23, 27) CSF receptors (EPO, GM-CSF, G-CSF) GH · prolactin · Oncostatin M · Leukemia inhibitory factor common subunits (Common gamma chain, common beta chain, gp130) Type II Interleukins (10, 20, 22, 28) · interferon (-α/β, -γ) Ig superfamily CSF1 · C-kit · IL-1 · IL-18 TNF CD27 · CD30 · CD40 · CD120 · Lymphotoxin β Chemokines IL-8 (α, β), CCR1,CXCR4 Other IL-17 · TGF-beta (1, 2) · Thrombopoietin Other endogenous Fc receptor Epsilon (ε) FcεRI · FcεRII Gamma (γ) FcγRI · FcγRII · FcγRIII · Neonatal Alpha (α)/mu (μ) FcαRI · Fcα/μR Lymphocyte homing receptor CD44 · L-selectin · integrin (VLA-4, LFA-1) Other Complement · Immunophilins (Cyclophilin) · Integrin · Killer-cell immunoglobulin-like · Scavenger Exogenous Pattern recognition/Toll-like TLR 1 · TLR 2 · TLR 3 · TLR 4 · TLR 5 · TLR 6 · TLR 7 · TLR 8 · TLR 9 · TLR 10 Antigen receptor B-cell · T cell Other Formyl peptide

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