Interleukin-19 is a cytokine that belongs to the IL-10 family of cytokines along with several other interleukins including IL-10, IL-20, IL-22, IL-24, IL-26, and several virus-encoded cytokines. It signals through the same cell surface receptor (IL-20R) that is used by IL-20 and IL-24. The IL-19 gene is expressed in resting monocytes and B cells. It is up-regulated in monocytes following stimulation with granulocyte-macrophage colony-stimulating factor (GM-CSF) or lipopolysaccharide.[1]
References
- ^ Chang, C. et al., Crystal Structure of Interleukin-19 Defines a New Subfamily of Helical Cytokines. Journal of Biological Chemistry, 2003, Volume 278, pages 3308-3313.
|
Cell signaling: cytokines |
|
| By family |
|
|
|
IL-1 superfamily
|
|
|
|
|
|
|
|
IL-10 family
|
|
|
|
|
|
|
|
|
|
|
|
IL-12 family
|
|
|
|
Other
|
|
|
|
|
|
|
|
|
|
|
Main
|
|
|
|
TNF (ligand) superfamily
|
|
|
|
|
|
|
|
|
|
|
|
|
| Other |
|
|
| By function |
|
|
This entry is from Wikipedia, the leading user-contributed encyclopedia. It may not have been reviewed by professional editors (see full disclaimer)
