Interleukin-22 receptor

interleukin 22 receptor, alpha 1
Identifiers
Symbol	IL22RA1
Alt. Symbols	IL22R
Entrez	58985
HUGO	13700
OMIM	605457
RefSeq	NM_021258
UniProt	A8K839
Other data
Locus	Chr. 1 p36.11

interleukin 22 receptor, alpha 2
Identifiers
Symbol	IL22RA2
Entrez	116379
HUGO	14901
OMIM	606648
RefSeq	NM_181310
UniProt	Q969J5
Other data
Locus	Chr. 6 q24.1-24.2

Interleukin-22 receptor is a type II cytokine receptor. It binds to Interleukin-22. It is a heterodimer of α1^[1] and α2^[2] subunits.

References

1. ^ Xie MH, Aggarwal S, Ho WH, Foster J, Zhang Z, Stinson J, Wood WI, Goddard AD, Gurney AL (2000). "Interleukin (IL)-22, a novel human cytokine that signals through the interferon receptor-related proteins CRF2-4 and IL-22R". J. Biol. Chem. 275 (40): 31335–9. doi:10.1074/jbc.M005304200. PMID 10875937. 
2. ^ Xu W, Presnell SR, Parrish-Novak J, Kindsvogel W, Jaspers S, Chen Z, Dillon SR, Gao Z, Gilbert T, Madden K, Schlutsmeyer S, Yao L, Whitmore TE, Chandrasekher Y, Grant FJ, Maurer M, Jelinek L, Storey H, Brender T, Hammond A, Topouzis S, Clegg CH, Foster DC (2001). "A soluble class II cytokine receptor, IL-22RA2, is a naturally occurring IL-22 antagonist". Proc. Natl. Acad. Sci. U.S.A. 98 (17): 9511–6. doi:10.1073/pnas.171303198. PMID 11481447. 

External links

• MeSH Receptors,+Interleukin-22

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v • d • e Transmembrane receptors: immune receptors Cytokine receptor Type I Interleukins (2, 3, 4, 5, 6, 7, 9, 11, 12, 13, 15, 21, 23, 27) CSF receptors (EPO, GM-CSF, G-CSF) GH · prolactin · Oncostatin M · Leukemia inhibitory factor common subunits (Common gamma chain, common beta chain, gp130) Type II Interleukins (10, 20, 22, 28) · interferon (-α/β, -γ) Ig superfamily CSF1 · C-kit · IL-1 · IL-18 TNF CD27 · CD30 · CD40 · CD120 · Lymphotoxin β Chemokines IL-8 (α, β), CCR1,CXCR4 Other IL-17 · TGF-beta (1, 2) · Thrombopoietin Other endogenous Fc receptor Epsilon (ε) FcεRI · FcεRII Gamma (γ) FcγRI · FcγRII · FcγRIII · Neonatal Alpha (α)/mu (μ) FcαRI · Fcα/μR Lymphocyte homing receptor CD44 · L-selectin · integrin (VLA-4, LFA-1) Other Complement · Immunophilins (Cyclophilin) · Integrin · Killer-cell immunoglobulin-like · Scavenger Exogenous Pattern recognition/Toll-like TLR 1 · TLR 2 · TLR 3 · TLR 4 · TLR 5 · TLR 6 · TLR 7 · TLR 8 · TLR 9 · TLR 10 Antigen receptor B-cell · T cell Other Formyl peptide

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