Interleukin-28 receptor

interleukin 28 receptor, alpha (interferon, lambda receptor)
Identifiers
Symbol	IL28RA
Alt. Symbols	CRF2/12, IFNLR, IL-28R1
Entrez	163702
HUGO	18584
OMIM	607404
RefSeq	NM_170743
UniProt	Q8IU57
Other data
Locus	Chr. 1 p36.11

interleukin 10 receptor, beta
Identifiers
Symbol	IL10RB
Alt. Symbols	CRFB4, D21S58, D21S66
Entrez	3588
HUGO	5965
OMIM	123889
RefSeq	NM_000628
UniProt	Q08334
Other data
Locus	Chr. 21 q22.1-22.2

Interleukin-28 receptor is a type II cytokine receptor. It binds interleukin-28. It consists of an α and shares a common β subunit the with interleukin-10 receptor.^[1][2]

References

1. ^ Kotenko SV, Gallagher G, Baurin VV, Lewis-Antes A, Shen M, Shah NK, Langer JA, Sheikh F, Dickensheets H, Donnelly RP (2003). "IFN-lambdas mediate antiviral protection through a distinct class II cytokine receptor complex". Nat. Immunol. 4 (1): 69–77. doi:10.1038/ni875. PMID 12483210. 
2. ^ Sheppard P, Kindsvogel W, Xu W, Henderson K, Schlutsmeyer S, Whitmore TE, Kuestner R, Garrigues U, Birks C, Roraback J, Ostrander C, Dong D, Shin J, Presnell S, Fox B, Haldeman B, Cooper E, Taft D, Gilbert T, Grant FJ, Tackett M, Krivan W, McKnight G, Clegg C, Foster D, Klucher KM (2003). "IL-28, IL-29 and their class II cytokine receptor IL-28R". Nat. Immunol. 4 (1): 63–8. doi:10.1038/ni873. PMID 12469119. 

External links

• MeSH Receptors,+Interleukin-28

This membrane protein-related article is a stub. You can help Wikipedia by expanding it.

v • d • e Transmembrane receptors: immune receptors Cytokine receptor Type I Interleukins (2, 3, 4, 5, 6, 7, 9, 11, 12, 13, 15, 21, 23, 27) CSF receptors (EPO, GM-CSF, G-CSF) GH · prolactin · Oncostatin M · Leukemia inhibitory factor common subunits (Common gamma chain, common beta chain, gp130) Type II Interleukins (10, 20, 22, 28) · interferon (-α/β, -γ) Ig superfamily CSF1 · C-kit · IL-1 · IL-18 TNF CD27 · CD30 · CD40 · CD120 · Lymphotoxin β Chemokines IL-8 (α, β), CCR1,CXCR4 Other IL-17 · TGF-beta (1, 2) · Thrombopoietin Other endogenous Fc receptor Epsilon (ε) FcεRI · FcεRII Gamma (γ) FcγRI · FcγRII · FcγRIII · Neonatal Alpha (α)/mu (μ) FcαRI · Fcα/μR Lymphocyte homing receptor CD44 · L-selectin · integrin (VLA-4, LFA-1) Other Complement · Immunophilins (Cyclophilin) · Integrin · Killer-cell immunoglobulin-like · Scavenger Exogenous Pattern recognition/Toll-like TLR 1 · TLR 2 · TLR 3 · TLR 4 · TLR 5 · TLR 6 · TLR 7 · TLR 8 · TLR 9 · TLR 10 Antigen receptor B-cell · T cell Other Formyl peptide

This entry is from Wikipedia, the leading user-contributed encyclopedia. It may not have been reviewed by professional editors (see full disclaimer)