Interleukin-29 (IL-29) is a protein of the helical cytokine family and is a type III interferon.[1] It is also known as IFNλ1 and is highly similar in amino acid sequence to the IL-28, the other type III interferon.
IL-29 plays an important role in host defenses against microbes and its gene is highly upregulated in cells infected with viruses.
The IL-29 gene is found on chromosome 19 in humans.[2]
References
- ^ Vilcek, Novel interferons. Nature Immunology, 2003, Volume 4, pages 8-9
- ^ P. Sheppard, et al., IL-28, IL-29 and their class II cytokine receptor IL-28R. Nature Immunology, 2003, Volume 4, pages 63-68.
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Cell signaling: cytokines |
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IL-12 family
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TNF (ligand) superfamily
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Cell signaling: cytokines |
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IL-1 superfamily
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IL-10 family
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IL-12 family
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Other
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Main
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TNF (ligand) superfamily
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