| Interstate 81 Main route of the Interstate Highway System in Tennessee |
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| Length: | 75.66 mi[1] (121.76 km) | ||||
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| South end: | |||||
| Major junctions: |
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| North end: | |||||
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Interstate 81 is an 824 mile long expressway stretching from Dandridge, Tennessee northward to the Thousand Islands Bridge at the United States-Canada border near Fishers Landing, New York. In Tennessee, Interstate 81 runs for 75 miles (121 km) from its southern terminus at Interstate 40 near Dandridge to the Virginia state line in Bristol.
Interstate 81 begins in Tennessee at Interstate 40 near Dandridge. I-81 parallels the Appalachian Mountains for most of Tennessee and Virginia. At mile marker 8, I-81 meets the eastern half of U.S. Route 25: U.S. Route 25E south of Morristown. I-81 doesn't go through either Johnson City or Kingsport; but at mile marker 57, I-81 meets Interstate 26 and U.S. Route 23 which go to Kingsport and Johnson City. At mile marker 75, I-81 leaves Tennessee and enters the commonwealth of Virginia.
| Major cities Bolded cities are officially-designated control cities for signs |
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| County | Location | Mile | # | Destinations | Notes |
|---|---|---|---|---|---|
| Jefferson | 0.0 | 1 | |||
| White Pine | 4.4 | 4 | |||
| Hamblen | 8.6 | 8 | No Trucks In Cumberland Gap Tunnel. | ||
| 12.4 | 12 | ||||
| 15.3 | 15 | Access to Copper Airport. | |||
| Greene | 23.1 | 23 | Access to Tusculum College. | ||
| 30.2 | 30 | ||||
| 36.2 | 36 | ||||
| 43.9 | 44 | Jearoldstown Rd | |||
| Washington | Fall Branch | 50.5 | 50 | ||
| Sullivan | Kingsport | 56 | Tri-Cities Crossing | ||
| 57.7 | 57 | ||||
| 59.4 | 59 | ||||
| 63.5 | 63 | Access to Tri-Cities Airport. | |||
| 66.1 | 66 | ||||
| Blountville | 69.6 | 69 | |||
| Bristol | 74.8 | 74 | Lee Highway. Signed as Exit 74A & 74B. | ||
| Virginia state line. I-81 continues into Virginia. | |||||
| Previous state: Terminus |
Tennessee | Next state: Virginia |
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