Isabela can refer to:
- Isabela II, Queen of Spain
- Isabela (province), in the Philippines
- Isabela, Negros Occidental in the Philippines.
- Isabela City in the Philippines.
- Isabela Island (Philippines) in the Philippines.
- Isabela, Puerto Rico
- Isabela Island (Galápagos) of the Galápagos Islands
- La Isabela in the Dominican Republic, first settlement of Columbus in the New World
See also
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