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Isoindole

 
Wikipedia: Isoindole
Isoindole
IUPAC name
Identifiers
CAS number [270-68-8]
PubChem 3013853
SMILES
Properties
Molecular formula C8H7N
Molar mass 117.15 g/mol
Except where noted otherwise, data are given for
materials in their standard state
(at 25 °C, 100 kPa)

Infobox references

Isoindole in heterocyclic chemistry is a benzo fused pyrrole.[1] The compound is an isomer of indole and its reduced form is an isoindoline.

In solution its tautomer without full aromaticity over the whole ring system is predominant:[citation needed]

Isoindole tautomerism

and therefore the compound resembles a pyrrole more than a simple imine. Isoindoles are building blocks for phthalocyanines which are relevant as dyes

Isoindole-1,3-diones

The commercially important phthalimide is an isoindole-1,3-dione with two carbonyl groups attached to the heterocyclic ring. Thalidomide is an infamous drug based on this framework.

See also

References

  1. ^ Heterocyclic chemistry T.L. Gilchrist ISBN 0852014220

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phthalocyanine
phthalocyanine pigments (organic chemistry)
indole

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