Acetaminophen; Dichloralphenazone; Isometheptene
Brand names: Amidrine®, Duradrin™, I.D.A.®, Midrin®, Migquin™, Migratine™, Migrazone™, Migrin-A, Va-Zone™
Chemical formula:
Acetaminophen; Dichloralphenazone; Isometheptene capsules
What are acetaminophen; dichloralphenazone; isometheptene capsules?
ACETAMINOPHEN; DICHLORALPHENAZONE; ISOMETHEPTENE (Amidrine®, Duradrin™, Midchlor®, Midrin®, Migquin™, Migratine™, Migrazone™, Migrex™, Mitride™) is a combination product used to migraine or tension-type headaches. Federal law prohibits the transfer of this drug to any person other than the patient for whom it was prescribed. Do not share this medicine with anyone else. Generic acetaminophen; dichloralphenazone; isometheptene capsules are available.
What should I tell my health care provider before I take this medicine?
They need to know if you have any of these conditions:
• bleeding or clotting problems
• diabetes mellitus
• drink more than 3 alcohol-containing drinks per day
• glaucoma
• head injury
• heart disease
• high blood pressure
• infection
• kidney disease
• liver disease
• lung problems
• porphyria
• skin problems
• stomach ulcer
• suppressed immune function
• thyroid disease
• an unusual or allergic reaction to acetaminophen, dichloralphenazone, isometheptene, other medicines, foods, dyes or preservatives
• pregnant or trying to get pregnant
• breast-feeding
How should I take this medicine?
Take acetaminophen; dichloralphenazone; isometheptene capsules by mouth at the first sign of a migraine headache. Follow the directions on the prescription label. Swallow the capsules with a drink of water, and follow with plenty of liquid. If taking for migraine headache, do not take more than 5 capsules in any 12-hour period. If taking for tension headache, do not take more than 8 capsules a day. Ask your prescriber how many capsules you should take per day. Stop using if headache worsens or continues for more than 48 hours.
This medicine is not for use in children.
What if I miss a dose?
If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.What drug(s) may interact with acetaminophen; dichloralphenazone; isometheptene?
• alcohol
• antacids
• antihistamines
• bromocriptine
• certain antibiotics
• cimetidine
• disulfiram
• entacapone
• medicines for anxiety or sleep problem
• medicines for mental problems and psychotic disturbances
• monoamine oxidase inhibitors (MAOIs) such as isocarboxazid and phenelzine - do not take acetaminophen; dichloralphenazone; isometheptene within 2 weeks of stopping MAOI therapy.
• omeprazole
• ritonavir
• tramadol
• warfarin
Tell your prescriber or health care professional about all other medicines that you are taking, including non-prescription medicines, nutritional supplements, or herbal products. Also tell your prescriber or health care professional if you are a frequent user of drinks with caffeine or alcohol, if you smoke, or if you use illegal drugs. These may affect the way your medicine works. Check with your health care professional before stopping or starting any of your medicines.
What should I watch for while taking acetaminophen; dichloralphenazone; isometheptene?
Many non-prescription medicines contain acetaminophen as an ingredient. To prevent accidental acetaminophen overdose, read labels carefully and do not take more than one product that contains acetaminophen. Report any possible overdose promptly to your prescriber or health care professional as soon as possible. The effects of excessive doses may not be obvious for several days.
Avoid drinking alcohol. Alcohol can make your headaches worse and increase the side effects of this medicine.
Acetaminophen; dichloralphenazone; isometheptene products can cause dizziness or drowsiness. Driving or operating machinery, or performing other tasks that require mental alertness requires caution when taking this medicine. You should not participate in these activities until you determine how this medicine affects you.
If you are receiving cancer chemotherapy or other immunosuppression medicine, do not take acetaminophen; dichloralphenazone; isometheptene without checking with your prescriber or health care professional. Acetaminophen; dichloralphenazone; isometheptene may hide the signs of an infection such as fever or pain.
Do not take acetaminophen; dichloralphenazone; isometheptene with other non-prescription medicines, especially cold and allergy medicines, without asking your prescriber or health care professional for advice.
What side effects may I notice from taking acetaminophen; dichloralphenazone; isometheptene?
Side effects that you should report to your prescriber or health care professional as soon as possible:
• difficulty breathing, wheezing
• fast or irregular breathing or heartbeat (palpitations)
• fever or sore throat
• redness, blistering, peeling or loosening of the skin, including inside the mouth
• skin rash or hives
• unusual bleeding or bruising
• unusual tiredness or weakness
• yellowing of the skin or eyes
Side effects that usually do not require medical attention (report to your prescriber or health care professional if they continue or are bothersome):
• dizziness
• drowsiness
• nausea
• mild upset stomach
Where can I keep my medicine?
Keep out of the reach of children in a container that small children cannot open. Do not share or give this medicine to anyone else.
Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Keep container tightly closed. Throw away any unused medicine after the expiration date.
Last updated: 7/1/2002
Important Disclaimer: The drug information provided here is for educational purposes only. It is intended to supplement, not substitute for, the diagnosis, treatment and advice of a medical professional. This drug information does not cover all possible uses, precautions, side effects and interactions. It should not be construed to indicate that this or any drug is safe for you. Consult your medical professional for guidance before using any prescription or over the counter drugs.
