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Janeway lesion

 
Medical Dictionary: Jane·way lesion
(jān'')
n.

A small erythematous or hemorrhagic lesion seen in some cases of bacterial endocarditis, usually on the palm or the sole.

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Wikipedia: Janeway lesion
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Janeway lesions are non-tender, small erythematous or haemorrhagic macular or nodular lesions on the palms or soles only a few millimeters in diameter that are pathognomonic of infective endocarditis.[1] Pathologically, the lesion is described to be a microabscess of the dermis with marked necrosis and inflammatory infiltrate not involving the epidermis, which is due to the deposition of circulating immune complexes in small blood vessels.[1]

Osler's nodes and Janeway lesions are similar, but Osler's nodes present with tenderness.[2]

Contents

Eponym

They are named after Edward G. Janeway (1841–1911), an American professor of medicine with interests in cardiology and infectious disease.[3]

See also

References

  1. ^ a b Farrior, J.B.; Silverman M.E. (1976). "A consideration of the differences between a Janeway's lesion and an Osler's node in infectious endocarditis". Chest. 70 (2): 239–43. doi:10.1378/chest.70.2.239. PMID 947688. 
  2. ^ Farrior JB, Silverman ME (August 1976). "A consideration of the differences between a Janeway's lesion and an Osler's node in infectious endocarditis". Chest 70 (2): 239–43. PMID 947688. http://www.chestjournal.org/cgi/pmidlookup?view=long&pmid=947688. 
  3. ^ Janeway C. (1998). "Presidential Address to The American Association of Immunologists. The road less traveled by: the role of innate immunity in the adaptive immune response". J. Immunol. 161 (2): 539–44. PMID 9670925. 

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Medical Dictionary. The American Heritage® Stedman's Medical Dictionary Copyright © 2002, 2001, 1995 by Houghton Mifflin Company Read more
Wikipedia. This article is licensed under the Creative Commons Attribution/Share-Alike License. It uses material from the Wikipedia article "Janeway lesion" Read more