Karyorrhexis

(cell and molecular biology) Fragmentation of a nucleus with scattering of the pieces in the cytoplasm.

A stage of cellular necrosis in which the fragments of the nucleus fragments and its chromatin are distributed irregularly throughout the cytoplasm.

Rupture of the cell nucleus in which the chromatin disintegrates into formless granules that are extruded from the cell.

Morphological characteristics of pyknosis and other forms of nuclear destruction

Apoptosis

Karyorrhexis is the destructive fragmentation of the nucleus of a dying cell^[1] whereby its chromatin is distributed irregularly throughout the cytoplasm. It is usually preceded by pyknosis and is followed by karyolysis and can occur either as a result of programmed cell death or necrosis.

See also

• Apoptosis
• Karyolysis

References

1. ^ Zamzami N, Kroemer G. (1999). "Apoptosis: Condensed matter in cell death". Nature 401 (127). http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=10490018. 

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