Ketoprofen tablets or capsules
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What do ketoprofen tablets or capsules do?
KETOPROFEN (Orudis® KT™, Oruvail®) is an anti-inflammatory drug. Ketoprofen helps relieve the inflammation and pain associated with rheumatoid arthritis, osteoarthritis, menstrual cramps or premenstrual pain and swelling. Ketoprofen is available in a non-prescription strength to treat minor aches and pains associated with the common cold, backache, muscular aches, toothache and menstrual pain. Generic ketoprofen immediate- and extended-release capsules are available.
What should I tell my health care provider before I take this medicine?
They need to know if you have any of these conditions:
• asthma, especially aspirin-sensitive asthma
• bleeding problems
• cigarette smoker
• coronary artery bypass graft (CABG) surgery within the past 2 weeks
• diabetes mellitus
• drink more than 3 alcohol-containing beverages a day
• heart or circulation problems like angina, high blood pressure, heart failure, heart rhythm problems, history of heart attack, history of blood clots, or leg edema (fluid retention)
• kidney disease
• liver disease
• lost a lot of fluid due to continued vomiting or diarrhea
• stomach or duodenal ulcers
• history of stroke
• systemic lupus erythematosus
• ulcerative colitis
• an unusual or allergic reaction to ketoprofen, aspirin, other salicylates, other NSAIDs, foods, dyes or preservatives
• pregnant or trying to get pregnant
• breast-feeding
How should I take this medicine?
Take ketoprofen tablets or capsules by mouth. Follow the directions on the label. Swallow tablets or capsules whole with a full glass of water; take tablets or capsules in an upright or sitting position. Taking a sip of water first, before taking the tablets or capsules, may help you swallow them. If possible take bedtime doses at least 10 minutes before lying down. Do not crush or chew the extended-release capsules. You can take ketoprofen with food to prevent stomach upset. Take your doses at regular intervals. Do not take your medicine more often or for a longer time than directed.
Contact your pediatrician or health care professional regarding the use of this medicine in children. Special care may be needed.
What other medicines can interact with ketoprofen?
• alcohol
• alendronate
• anti-inflammatory drugs (other NSAIDs, prednisone)
• aspirin and aspirin-like medicines
• cidofovir
• cyclosporine
• drospirenone; ethinyl estradiol (Yasmin®)
• entecavir
• herbal products that contain feverfew, garlic, ginger, or ginkgo biloba
• lithium
• medicines for high blood pressure
• medicines that affect platelets
• medicines that treat or prevent blood clots such as warfarin and other 'blood thinners'
• methotrexate
• pemetrexed
• water pills (diuretics)
Tell your prescriber or health care professional about all other medicines you are taking, including non-prescription medicines, nutritional supplements, or herbal products. Also tell your prescriber or health care professional if you are a frequent user of drinks with caffeine or alcohol, if you smoke, or if you use illegal drugs. These may affect the way your medicine works. Check with your health care professional before stopping or starting any of your medicines.
What do I need to watch for while I take ketoprofen?
Let your prescriber or health care professional know if your pain continues, do not take with other pain medicines or fever medicine without advice. If you get flu-like symptoms (fever, chills, muscle aches and pains), call your prescriber or health care professional. Do not treat yourself.
To reduce unpleasant effects on your throat and stomach, take ketoprofen with a full glass of water and never just before lying down. Take ketoprofen with food or milk if stomach upset occurs. If you notice black, tarry stools or experience severe stomach pain and vomit blood or what looks like coffee grounds, notify your health care prescriber immediately. If you have stomach pain or an upset stomach that worsens or persists, redness or swelling in a painful area, or any new symptoms, call your health care professional.
If you are taking medicines that affect the clotting of your blood, such as aspirin or blood thinners such as Coumadin®, talk to your health care provider or prescriber before taking this medicine.
You may get dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how ketoprofen affects you. Do not sit or stand up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells.
Do not smoke cigarettes or drink alcohol; these increase irritation to your stomach and can make it more susceptible to damage from ketoprofen.
It is especially important not to use ketoprofen during the last 3 months of pregnancy unless specifically directed to do so by your health care provider. Ketoprofen may cause problems in the unborn child or complications during delivery.
If you are going to have surgery, tell your prescriber or health care professional that you are taking ketoprofen. Problems can arise if you need dental work, and in the day to day care of your teeth. Try to avoid damage to your teeth and gums when you brush or floss your teeth.
What side effects may I notice from taking ketoprofen?
Side effects that you should report to your prescriber or health care professional as soon as possible:
• signs of bleeding - black tarry stools, blood in the urine, unusual tiredness or weakness, vomiting blood or vomit that looks like coffee grounds
• signs of an allergic reaction - difficulty breathing, wheezing, skin rash, redness, blistering or peeling skin, hives, itching, swelling of eyelids, throat, lips
• blurred vision
• change in the amount of urine passed
• difficulty swallowing, severe heartburn or burning, pain in throat
• pain or difficulty passing urine
• stomach pain or cramps
• swelling of feet or ankles
Side effects that usually do not require medical attention (report to your prescriber or health care professional if they continue or are bothersome):
• diarrhea or constipation
• dizziness, drowsiness
• gas or heartburn
• headache
• nausea, vomiting
Where can I keep my medicine?
Keep out of the reach of children in a container that small children cannot open.
Store at room temperature, approximately 25 degrees C (77 degrees F) away from humidity (not in the bathroom or kitchen, if possible). Keep container tightly closed. Throw away any unused medicine after the expiration date.
Important Disclaimer: The drug information provided here is for educational purposes only. It is intended to supplement, not substitute for, the diagnosis, treatment and advice of a medical professional. This drug information does not cover all possible uses, precautions, side effects and interactions. It should not be construed to indicate that this or any drug is safe for you. Consult your medical professional for guidance before using any prescription or over the counter drugs.
