Klinefelter Syndrome: Prognosis

While many men with Klinefelter syndrome go on to live normal lives, nearly 100% of these men will be sterile (unable to produce a child). However, a few men with Klinefelter syndrome have been reported who have fathered a child through the use of assisted fertility services. Males with Klinefelter syndrome have an increased risk of several conditions such as osteoporosis, autoimmune disorders such as lupus and arthritis, diabetes and both breast and germ cell tumors.

— Carin Lea Beltz, M.S.