lacteal

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(lăk'tē-əl) pronunciation
adj.
  1. Of, relating to, or resembling milk.
  2. Anatomy. Of or relating to any of numerous minute intestinal lymph-carrying vessels that convey chyle from the intestine to lymphatic circulation and thereby to the thoracic duct.
n. Anatomy
A lacteal vessel.

[From Latin lacteus, from lac, lact-, milk.]

lacteally lac'te·al·ly adv.

A central, blind-ended lymph vessel in a villus into which neutral fat is passed from the columnar epithelium of the small intestine where the fat has been resynthesized from fatty acids and glycerol. The fat is in the form of a white, milky emulsion (hence, the name lacteal) and is carried to all parts of the body.

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IN BRIEF: Of or like milk. Also: A lymphatic vessel in the small intestine.

pronunciation The river was lacteal in nature because it had much glacial material in it.

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  1. of, relating to, or resembling milk; milky.
  2. (of lymph vessels) containing or conveying chyle.
  3. any blind-ended lymph vessel that carries chyle from a villus of the small intestine to the thoracic duct.

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1. pertaining to milk.
2. any of the intestinal lymphatics that transport chyle.

Lacteal
Gray1060.png
Transverse section of a villus, from the human intestine. X 350.
a. Basement membrane, here somewhat shrunken away from the epithelium.
b. Lacteal.
c. Columnar epithelium.
d. Its striated border.
e. Goblet cells.
f. Leucocytes in epithelium.
f’. Leucocytes below epithelium.
g. Bloodvessels.
h. Muscle cells cut across.
Gray1061.png
Villi of small intestine, showing bloodvessels and lymphatic vessels.

A lacteal is a lymphatic capillary that absorbs dietary fats in the villi of the small intestine.

Triglycerides are emulsified by bile and hydrolyzed by the enzyme lipase, resulting in a mixture of fatty acids and monoglycerides.[1] These then pass from the intestinal lumen into the enterocyte, where they are re-esterified to form triacylglycerol. The triacylglycerol is then combined with phospholipids, cholesterol ester, and apolipoprotein B-48 to form chylomicrons. These chylomicrons then pass into the lacteals, forming a milky substance known as chyle. The lacteals merge to form larger lymphatic vessels that transport the chyle to the thoracic duct where it is emptied into the bloodstream at the subclavian vein.[2][3]

At this point, the fats are in the bloodstream in the form of chylomicrons. Once in the blood, chylomicrons are subject to delipidation by lipoprotein lipase. Eventually, enough lipid has been lost and additional apolipoproteins gained, that the resulting particle (now referred to as a chylomicron remnant) can be taken up by the liver. From the liver, the fat released from chylomicron remnants can be re-exported to the blood as the triglyceride component of very low density lipoprotein (VLDL). VLDL, also subject to delipidation by vascular lipoprotein lipase, delivers fats to tissues throughout the body and, in particular, the released fatty acids can be stored in adipose cells as triglycerides. As triglycerides are lost from VLDL the lipoprotein particle becomes smaller and denser (since protein is denser than lipid) and ultimately becomes low density lipoprotein (LDL). A lot has been written about LDL because it is thought to be atherogenic.

Note that in contrast to any other route of absorption from the small intestine, the lymphatic system avoids first pass metabolism.

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