Leukocidin

A substance produced by some pathogenic bacteria that is toxic to polymorphonuclear leukocytes (neutrophils).

A leukocidin is a type of cytotoxin created by some types of bacteria. It is a type of pore forming toxin. Leukocidins get their names by killing ("-cide") leukocytes.

One type is Panton-Valentine leukocidin.

External links

• MeSH Leukocidins
• Leukocidin at eMedicine Dictionary
• UMich Orientation of Proteins in Membranes families/superfamily-35

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v • d • e Toxins (enterotoxin/neurotoxin/hemotoxin/cardiotoxin) Bacterial toxins Exotoxin Gram positive Bacilli Clostridium: tetani (Tetanospasmin) · perfringens (Alpha toxin, Enterotoxin) · difficile (A, B) · botulinum (Botox) other: Anthrax toxin · Listeriolysin O Cocci Streptolysin · Leukocidin (Panton-Valentine leukocidin) · Staphylococcus (Staphylococcus aureus alpha/beta/delta, Exfoliatin, Toxic shock syndrome toxin, SEB) Actinobacteria Cord factor · Diphtheria toxin Gram negative Shiga toxin · Verotoxin/shiga-like toxin (E. coli) · E. coli heat-stable enterotoxin/enterotoxin · Cholera toxin · Pertussis toxin · Pseudomonas exotoxin · Extracellular adenylate cyclase By mechanism type I (Superantigen) · type II (Pore forming toxins) · type III (AB toxin/AB5) Endotoxin Lipopolysaccharide (Lipid A) · Bacillus thuringiensis delta endotoxin Virulence factor Clumping factor A · Fibronectin binding protein A Mycotoxins Aflatoxin · Amatoxin (Alpha-amanitin, Beta-amanitin, Gamma-amanitin, Epsilon-amanitin) · Citrinin · Cytochalasin · Ergotamine · Fumonisin (Fumonisin B1, Fumonisin B2) · Gliotoxin · Ibotenic acid · Muscimol · Ochratoxin · Patulin · Sterigmatocystin · Trichothecene · Vomitoxin · Zeranol · Zearalenone Invertebrates arthropod: scorpion: Charybdotoxin, Maurotoxin, Agitoxin, Margatoxin, Slotoxin, Scyllatoxin, Hefutoxin · spider: Latrotoxin (Alpha-latrotoxin) · Stromatoxin · PhTx3 mollusca: Conotoxin · Eledoisin · Onchidal · Saxitoxin Vertebrates fish: Ciguatera · Tetrodotoxin amphibian: (+)-Allopumiliotoxin 267A · Batrachotoxin · Bufotoxins (Arenobufagin, Bufotalin, Bufotenin · Cinobufagin, Marinobufagin) · Epibatidine · Histrionicotoxin · Pumiliotoxin 251D · Tarichatoxin reptile/snake venom: Bungarotoxin (Alpha-Bungarotoxin, Beta-Bungarotoxin) · Calciseptine · Taicatoxin · Calcicludine · Cardiotoxin III note: some toxins are produced by lower species and pass through intermediate species

v • d • e Protein: membrane proteins / membrane glycoproteins / integral membrane proteins Transmembrane protein Transmembrane receptors (CD33) Peripheral membrane protein Lipid anchored protein Pore-forming toxin antimicrobial cationic peptide (Cathelicidin, Cecropin, Defensin, Dermcidin, Histatin, Magainin, Melitten, Polymyxin, Thionin) · Bacteriocin · Gramicidin (Gramicidin S) · Hemolysin · Leukocidin · Perforin · Streptolysin Transfer/transport Membrane transport proteins · Phospholipid transfer proteins · Vesicular transport proteins Cytoskeleton Ankyrin · Dystrophin · Spectrin · Utrophin Ungrouped Arrestin · Calnexin · Connexin · Ephrin · Heterotrimeric GTP-binding proteins · LDL-receptor-related protein associated protein · Membrane fusion protein (VAMP) · Myelin basic protein · Neurofibromin 2 · Presenilin (PSEN1, PSEN2) · Protoporphyrinogen oxidase · pulmonary surfactant (Pulmonary surfactant-associated protein B, Pulmonary surfactant-associated protein C) · Tetraspanin · Peroxin

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