Leukotriene A4

Leukotriene A4
Identifiers
CAS number	[72059-45-1]
PubChem	5280383
MeSH	Leukotriene+A4
Properties
Molecular formula	C20H30O3
Molar mass	318.45 g/mol
Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa) Infobox references

Leukotriene A4 is a leukotriene.

Leukotriene A4 hydrolase converts it to Leukotriene B4.

Eicosanoid synthesis. (Leukotrienes at right.)

v • d • e Autacoids, unsaturated fatty acids: Eicosanoids Precursor Arachidonic acid Prostanoids Prostaglandins (PG) and analogues Precursor H2 Active D/J D2 E/F E2 (Dinoprostone): Enprostil · Sulprostone E1 (Alprostadil): Misoprostol · Gemeprost F2α (Dinoprost): Bimatoprost · Carboprost · Latanoprost · Tafluprost · Travoprost · Unoprostone I I2 (Prostacyclin/Epoprostenol): Beraprost · Iloprost · Treprostinil Thromboxanes (TX) A2 · B2 Leukotrienes (LT) Precursor Arachidonic acid 5-hydroperoxide Initial A4 · B4 SRS-A C4 · D4 · E4 Nonclassic Lipoxins (A4, B4) · Virodhamine By function bronchoconstriction (PGF2α, TXA2, LTC4, LTD4, LTE4) vasoconstriction (PGF2α, TXA2, TXB2) · vasodilation (PGE2, PGI2, LTC4, LTD4, LTE4) platelets: induce (TXA2) inhibit (PGD2, PGI2) · leukocytes: induce (TXA2, LTB4) inhibit (PGD2, PGE2) labor stimulation: (PGE2 (Dinoprostone), PGF2α (Dinoprost)) see also enzymes

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