Leukotriene E4 is a leukotriene.
Eicosanoid synthesis. (Leukotrienes at right.)
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Autacoids, unsaturated fatty acids: Eicosanoids |
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| Precursor |
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| Prostanoids |
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| Leukotrienes (LT) |
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| Nonclassic |
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| By function |
bronchoconstriction ( PGF2α, TXA2, LTC4, LTD4, LTE4)
vasoconstriction (PGF2α, TXA2, TXB2) · vasodilation (PGE2, PGI2, LTC4, LTD4, LTE4)
platelets: induce (TXA2) inhibit (PGD2, PGI2) · leukocytes: induce (TXA2, LTB4) inhibit (PGD2, PGE2)
labor stimulation: ( PGE2 (Dinoprostone), PGF2α (Dinoprost))
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