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| Limb bud | |
|---|---|
| Days | 29 |
| Precursor | lateral plate mesoderm |
In embryology, the limb bud is a structure formed by the developing limb, derived from lateral plate mesoderm[citation needed]. It is intimately related with the apical ectodermal ridge, which secretes factors (fibroblast growth factors [FGF] for example) inducing the initial differentiation of the limb bud. In turn, the mesodermal tissue of the limb bud secretes factors sustaining the development of the Apical Ectodermal Ridge.
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