louse up

verb

To harm irreparably through inept handling; make a mess: ball up, blunder, boggle, botch, bungle, foul up, fumble, gum up, mess up, mishandle, mismanage, muddle, muff, spoil. Informal bollix up, muck up. Slang blow¹, goof up, screw up, snafu. Idioms: make a muck of. See correct/incorrect, help/harm/harmless.

Spoil, ruin, bungle. For example, The bad weather loused up our plans, or Your change of mind really loused me up. This slangy expression originated in World War I, when infestation with lice was the common lot of soldiers in the trenches; its figurative use dates from the 1930s.

The verb has one meaning:

Meaning #1: make a mess of, destroy or ruin
  Synonyms: botch, bumble, fumble, botch up, muff, blow, flub, screw up, ball up, spoil, muck up, bungle, fluff, bollix, bollix up, bollocks, bollocks up, bobble, mishandle, foul up, mess up, fuck up