Lumefantrine: Information from Answers.com


Lumefantrine
Systematic (IUPAC) name
2-(dibutylamino)-1-[(9E)-2,7-dichloro-9-(4-chlorobenzylidene)-9H-fluoren-4-yl]ethanol
Identifiers
CAS number	82186-77-4
ATC code	?
PubChem	5311253
Chemical data
Formula	C₃₀H₃₂Cl₃N O
Mol. mass	528.939 g/mol
Pharmacokinetic data
Bioavailability	?
Metabolism	?
Half life	?
Excretion	?
Therapeutic considerations
Pregnancy cat.	?
Legal status
Routes	?

Lumefantrine (or benflumetol) is an antimalarial drug.

The term "co-artemether" is sometimes used to describe the administration of lumefantrine with artemether.^[1]

References

^ Toovey S, Jamieson A, Nettleton G (2003). "Successful co-artemether (artemether-lumefantrine) clearance of falciparum malaria in a patient with severe cholera in Mozambique". Travel medicine and infectious disease 1 (3): 177–9. doi:10.1016/j.tmaid.2003.09.002. PMID 17291911.

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Cryptosporidiosis	thiazole (Nitazoxanide)

Isosporiasis	Co-trimoxazole^#

Toxoplasmosis	Pyrimethamine • Sulfadiazine

Qs: Amino-	4-Aminoquinoline (Amodiaquine^#, Chloroquine^#, Hydroxychloroquine) • 8-Aminoquinoline (Primaquine^#, Pamaquine)

Qs: Methanol-	Mefloquine^# • Quinine^# • Quinidine

Other	Halofantrine • amyl alcohol (Lumefantrine^#)

DRIs	diaminopyridines (Pyrimethamine^#) • biguanides (Proguanil^#, Cycloguanil)

DSIs	Sulfadoxine^#

PfATP6 inhibitor

Other

aminoacridine (Quinacrine) • ubiquinone analogue (Atovaquone) • tetracycline (Doxycycline^#)

Combinations

Trypanosomiasis	African trypanosomiasis: Eflornithine^# · Melarsoprol^# · Pentamidine^# · Suramin^# Chagas disease: Benznidazole^# · Nifurtimox^#

Leishmaniasis	Amphotericin B^# · Pentavalent antimonials (Meglumine antimoniate^#, Sodium stibogluconate) · Pentamidine^# · Miltefosine · Paromomycin

PAM	Amphotericin B

Giardiasis	nitrofuran (Furazolidone) · azole (Metronidazole^#, Albendazole, Tinidazole) · thiazole (Nitazoxanide) · aminoacridine (Quinacrine)

Trichomoniasis	azole (Metronidazole^#, Tinidazole)

Dientamoebiasis	Iodoquinol · Doxycycline · Metronidazole · Paromomycin · Secnidazole

^#WHO-EM. ^†Undergoing clinical trials, not FDA approved. ^‡Withdrawn from market. ^§Development halted.
see also diseases

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	Coartem
	Chlorproguanil hydrochloride-dapsone-artesunate
	Artemether

	How can you test the active strength of lumefantrine and artemether in 01 tablet?
	How can you test the active strength of lumefantrine and artemether in 01 tablet?