Medical Encyclopedia:

Lymph Node Biopsy: Purpose

The lymph system is the body's primary defense against infection. It consists of the spleen, tonsils, thymus, lymph nodes, lymph vessels, and the clear, slightly yellow fluid called lymph. These components produce and transport white blood cells called lymphocytes and macrophages that rid the body of infection. The lymph system is also involved in the production of antibodies. Antibodies are proteins that fight bacteria, viruses, and other foreign materials that enter the body.

The lymph vessels are similar to veins, only instead of carrying blood as veins do, they circulate lymph to most tissues in the body. Lymph nodes are about 600 small, bean-shaped collections of tissue found along the lymph vessel. They produce cells and proteins that fight infection, and clean and filter lymph. Lymph nodes are sometimes called lymph glands, although they are not true glands. When someone talks about having swollen glands, they are actually referring to lymph nodes.

Normal lymph glands are no larger than 0.5 in (1.3 cm) in diameter and are difficult to feel. However, lymph nodes can enlarge to greater than 2.5 in (6 cm) and can become sore. Most often the swelling is caused by an infection, but it can also be caused by cancer.

Cancers can metastasize (spread) through the lymph system from the site of the original tumor to distant parts of the body where secondary tumors are formed. The purpose of a lymph node biopsy is to determine the cause of the swelling and/or to see if cancer has begun to spread through the lymph system. This information is important in staging the cancer and devising a treatment plan.

— Tish Davidson



 
 
 

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