Pertaining to or emanating from lysosomes.
- l. enzymes — enzymes located in the lysosomes.
- l. phospholipidosis — overloading of lysosomes with phospholipids as caused by the inhibition of phospholipidases by aminoglycosides.
- l. storage diseases — diseases in which there is a congenital or acquired deficiency of an enzyme so that one or more specific metabolic processes are not completed. As a result there is an accumulation of metabolic products in the cellular lysosomes. The histological lesion indicates the error in function but not the cause. Most of these diseases are inherited but swainsonine poisoning is caused by plant (Swainsona, Astragalus, Trachyandra spp.) poisoning. See also ceroid lipofuscinosis, glycogenosis, glycoproteinosis, lipid storage disease, mucopolysaccharidosis.
