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lipase A, lysosomal acid, cholesterol esterase (Wolman disease)
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| Identifiers | |
| Symbol | LIPA |
| Entrez | 3988 |
| HUGO | 6617 |
| OMIM | 278000 |
| RefSeq | NM_000235 |
| UniProt | P38571 |
| Other data | |
| EC number | 3.1.1.3 |
| Locus | Chr. 10 q23.2-23.3 |
Lysosomal lipase is a form of lipase which functions intracellularly, in the lysosomes.
Clinical significance
A deficiency is associated with Wolman disease.
Chlorpromazine is an inhibitor of lysosomal lipase.[1]
References
- ^ Sauro VS, Klamut HJ, Lin CH, Strickland KP (1985). "Lysosomal triacylglycerol lipase activity in L6 myoblasts and its changes on differentiation". Biochem. J. 227 (2): 583–9. PMID 4004781.
External links
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