n., pl., -ses (-sēz).
The presence of macrocytes in the blood.
macrocytotic mac'ro·cy·tot'ic (-tŏt'ĭk) adj.
macrocytosis
Dictionary:
mac·ro·cy·to·sis (măk'rō-sī-tō'sĭs)  |
| 5min Related Video: macrocytosis |
| WordNet: macrocytosis |
Note: click on a word meaning below to see its connections and related words.
The noun has one meaning:
Meaning #1:
the presence of macrocytes in the blood
| Wikipedia: Macrocytosis |
| Macrocytosis | |
|---|---|
| Classification and external resources | |
| ICD-10 | D75.8 |
| ICD-9 | 289.89 |
| DiseasesDB | 7688 |
| eMedicine | med/1381 |
Macrocytosis is the enlargement of red blood cells with near-constant hemoglobin concentration, and is defined by a mean corpuscular volume (MCV) of greater than 100 femtolitres (the precise criterion varies between laboratories).
Causes
Most commonly (especially when the increase in size is mild, and just above normal range) the etiology is bone marrow dysplasia primary to alcohol abuse and Chronic alcoholism. Other causes may include:
- Megaloblastosis (Vitamin B12 or folate deficiency; or DNA synthesis-inhibiting drugs)
- hypothyroidism
- reticulocytosis (commonly from hemolysis or a recent history of blood loss).
- liver disease
- myeloproliferative disease
Complications
No complications arise from macrocytosis itself and a prognosis will be determined from its etiology.
See also
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 | Dictionary. The American Heritage® Dictionary of the English Language, Fourth Edition Copyright © 2007, 2000 by Houghton Mifflin Company. Updated in 2009. Published by Houghton Mifflin Company. All rights reserved. Read more |
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| WordNet. WordNet 1.7.1 Copyright © 2001 by Princeton University. All rights reserved. Read more |
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| Wikipedia. This article is licensed under the Creative Commons Attribution/Share-Alike License. It uses material from the Wikipedia article "Macrocytosis". Read more |
