(medicine) Enlargement of the tongue.
Macroglossia
| Sci-Tech Dictionary: macroglossia |
(′mak·rō′gläs·ē·ə)
| 5min Related Video: Macroglossia |
| Dental Dictionary: macroglossia |
(mak'rōglōs'ē ə)
n
n
An enlarged tongue resulting from muscle hypertrophy, vascular or neurogenic tumor, or endocrine disturbance.
Macroglossia. (Sapp/Eversole/Wysocki, 2004)
| Veterinary Dictionary: macroglossia |
Excessive size of the tongue.
| Wikipedia: Macroglossia |
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This article needs additional citations for verification. Please help improve this article by adding reliable references. Unsourced material may be challenged and removed. (March 2009) |
| Macroglossia | |
|---|---|
| Classification and external resources | |
| ICD-10 | Q38.2 |
| ICD-9 | 529.8 |
| OMIM | 153630 |
| DiseasesDB | 7689 |
| eMedicine | ent/746 |
| MeSH | [1] |
Macroglossia is the medical term for unusual enlargement (hypertrophy) of the tongue. Severe enlargement of the tongue can cause cosmetic and functional difficulties including in speaking, eating, swallowing and sleeping.
Causes
Macroglossia is common in primary and myeloma-related amyloidosis.[citation needed] Amyloidosis is an accumulation of insoluble proteins in tissues that impedes normal function.[1]
Macroglossia is also a clinical feature in congenital hypothyroidism,[2] rare genetic syndromes such as Beckwith-Wiedemann syndrome[3] and immunodeficiency, centromere instability and facial anomalies syndrome, acromegaly and Hurler syndrome.[citation needed]
Apparent macroglossia can also occur in Down syndrome.[4]
References
- ^ Merck Manual 17th Ed.
- ^ Grant DB, Smith I, Fuggle PW, Tokar S, Chapple J (January 1992). "Congenital hypothyroidism detected by neonatal screening: relationship between biochemical severity and early clinical features". Arch. Dis. Child. 67 (1): 87–90. PMID 1739345.
- ^ Clauser L, Tieghi R, Polito J (March 2006). "Treatment of macroglossia in Beckwith-Wiedemann syndrome". J Craniofac Surg 17 (2): 369–72. PMID 16633192. http://meta.wkhealth.com/pt/pt-core/template-journal/lwwgateway/media/landingpage.htm?an=00001665-200603000-00030.
- ^ Guimaraes CV, Donnelly LF, Shott SR, Amin RS, Kalra M (October 2008). "Relative rather than absolute macroglossia in patients with Down syndrome: implications for treatment of obstructive sleep apnea". Pediatr Radiol 38 (10): 1062–7. doi:. PMID 18685841. http://dx.doi.org/10.1007/s00247-008-0941-7.
External links
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 | Sci-Tech Dictionary. McGraw-Hill Dictionary of Scientific and Technical Terms. Copyright © 2003, 1994, 1989, 1984, 1978, 1976, 1974 by McGraw-Hill Companies, Inc. All rights reserved. Read more |
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| Dental Dictionary. Mosby's Dental Dictionary. Copyright © 2004 by Elsevier, Inc. All rights reserved. Read more |
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| Veterinary Dictionary. Saunders Comprehensive Veterinary Dictionary 3rd Edition. Copyright © 2007 by D.C. Blood, V.P. Studdert and C.C. Gay, Elsevier. All rights reserved. Read more |
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| Wikipedia. This article is licensed under the Creative Commons Attribution/Share-Alike License. It uses material from the Wikipedia article "Macroglossia". Read more |
