City (pop., 2000: 107,006), southern New Hampshire, U.S. Located on the
Merrimack River, it is the state's largest city. It was settled in 1722 – 23 and incorporated as the town of Derryfield in 1751. One of America's first textile mills was built there in 1805, beginning a period of rapid industrial growth. Renamed Manchester in 1810, it was incorporated as a city in 1846. Canal systems built in the early 19th century opened navigation to
Boston. The textile industry's decline in the 1930s spurred industrial diversification. It is the seat of St. Anselm College, Notre Dame College, and New Hampshire College.
For more information on Manchester, visit Britannica.com.