Margin of safety

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(′mär·jən əv ′sāf·tē)

(design engineering) A design criterion, usually the ratio between the load that would cause failure of a member or structure and the load that is imposed upon it in service.



n.

The amount between a therapeutic dose and a lethal dose of a drug.

The safety factor, expressed either in a percentage or a ratio, by which the ultimate failing load of components exceeds the design limit load.

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n

The margin between lethal and toxic doses.

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Margin of safety

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