Mechanical hemolytic anemia
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Mechanical hemolytic anemia
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It has been suggested that March hemoglobinuria be merged into this article or section. (Discuss) Proposed since May 2012. |
Mechanical hemolytic anemia is a form of hemolytic anemia due to mechanically induced damage to red blood cells. Red blood cells, while flexible, may in some circumstances succumb to physical shear and compression.[1] This may result in hemoglobinuria. Some forms are self-inflicted (march hemoglobinuria),[2] if not intentionally, through repeated mechanical motions. Examples include marathon running, prolonged marching, and bongo drumming.[3] The other common form, called microangiopathic hemolytic anemia, is a chronic condition due to prosthetic heart valves.[1]
References
- ^ a b Dan L. Longo, Harrison's Hematology and Oncology, 2010, ISBN 0-07-166335-5; page 121.
- ^ Anthony S. Fauci, Eugene Braunwald, Dennis Kasper, Stephen Hauser, Dan L. Longo, Harrison's Manual of Medicine, page 328, 2009, ISBN 0-07-147743-8.
- ^ Reinhold Munker, Erhard Hiller, Jonathan Glass, Ronald Paquette, Modern Hematology: Biology and Clinical Management, 2007, page 126, ISBN 1-58829-557-5.
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