mediator
American Heritage Dictionary:
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me·di·a·tor
(mē'dē-ā'tər) 
n.
n.
- One that mediates, especially one that reconciles differences between disputants.
- Physiology. A substance or structure that mediates a specific response in a bodily tissue.
Roget's Thesaurus:
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mediator
noun
- Someone who acts as an intermediate agent in a transaction or helps to resolve differences: broker, go-between, interceder, intercessor, intermediary, intermediate, intermediator, middleman. See means.
Antonyms by Answers.com:
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mediator
n
Definition: person who negotiates agreement
Antonyms: arguer, fighter
Oxford Dictionary of Biochemistry:
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mediator
or MED
a multiprotein complex (20 — 30 polypeptides, ≈2 MDa) that acts as a transcriptional coactivator of yeast. It bridges general initiation factors that bind to promoters of protein genes, and the C-terminal domain of the largest subunit of RNA polymerase II. The complex is distinct from that composed of general transcriptional activators, or of upstream stimulatory activity (USA) factors. Several mammalian complexes that have mediator-like transcriptional activity have been characterized. The human equivalents are TRAP and SMCC.
a multiprotein complex (20 — 30 polypeptides, ≈2 MDa) that acts as a transcriptional coactivator of yeast. It bridges general initiation factors that bind to promoters of protein genes, and the C-terminal domain of the largest subunit of RNA polymerase II. The complex is distinct from that composed of general transcriptional activators, or of upstream stimulatory activity (USA) factors. Several mammalian complexes that have mediator-like transcriptional activity have been characterized. The human equivalents are TRAP and SMCC.
| mediated transport, mediated diffusion, median lethal dose | |
| medical, medical subject headings, medicinal |
Random House Word Menu:
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categories related to 'mediator'
- Judges, Lawyers, and Others in the Court System - mediator: person who settles disputes and serves as intermediary between parties
- Employers, Employees, and Business People - mediator: outsider brought in to settle dispute
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Copyrights:
American Heritage Dictionary
The American Heritage® Dictionary of the English Language, Fourth Edition Copyright © 2007, 2000 by Houghton Mifflin Company. Updated in 2009. Published by Houghton Mifflin Company. All rights reserved.
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Roget's Thesaurus
Roget's II: The New Thesaurus, Third Edition by the Editors of the American Heritage® Dictionary Copyright © 1995 byHoughton Mifflin Company. Published by Houghton Mifflin Company. All rights reserved.
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Oxford Dictionary of Biochemistry
Oxford University Press. Oxford Dictionary of Biochemistry and Molecular Biology © 1997, 2000, 2006 All rights reserved.
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