Megakaryoblast

The precursor of a megakaryocyte.

The earliest cytologically identifiable precursor in the thrombocytic series, which matures to form the promegakaryocyte.

Haematopoiesis

A megakaryoblast is a precursor cell to a promegakaryocyte, which in turn becomes a megakaryocyte during haematopoiesis. It is the beginning of the thrombocytic series.

It derives from a CFU-Me colony unit of pluripotential hemopoietic stem cells. (Some sources use the term "CFU-Meg" to identify the CFU.^[1])

References

1. ^ Ganong, William F.; McPhee, Stephen J.; Lingappa, Vishwanath R. (2005). Pathophysiology of Disease: An Introduction to Clinical Medicine (Lange). McGraw-Hill Medical. pp. 107. ISBN 0-07-144159-X. 

External links

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v • d • e Blood physiology Haematopoiesis Lymphopoiesis Lymphoblast · Prolymphocyte Myelopoiesis (CFU-GEMM) CFU-GM Granulopoiesis (Myeloblast, Promyelocyte, Myelocyte, Metamyelocyte, Band cell) Monocytopoiesis (Monoblast, Promonocyte) MEP Thrombopoiesis (Megakaryoblast, Promegakaryocyte) Erythropoiesis (Proerythroblast, Normoblast, Reticulocyte) General Extramedullary hematopoiesis Hemostasis Coagulation (Fibrinolysis) · Clot retraction · Platelet adhesiveness

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