mess up

The verb has 3 meanings:

Meaning #1: make a mess of, destroy or ruin
  Synonyms: botch, bumble, fumble, botch up, muff, blow, flub, screw up, ball up, spoil, muck up, bungle, fluff, bollix, bollix up, bollocks, bollocks up, bobble, mishandle, louse up, foul up, fuck up

Meaning #2: disturb the smoothness of
  Synonyms: ruffle, ruffle up, rumple

Meaning #3: make a mess of or create disorder in
  Synonym: mess