Metahexamide

Metahexamide
IUPAC name 1-(3-amino-4-methylphenyl)sulfonyl-3-cyclohexylurea
Identifiers
CAS number	565-33-3 Y
PubChem	11259
ChEMBL	CHEMBL507419 N
ATC code	A10BB10
Jmol-3D images	Image 1
SMILES CC1=C(C=C(C=C1)S(=O)(=O)NC(=O)NC2CCCCC2)N
Properties
Molecular formula	C14H21N3O3S
Molar mass	311.4 g/mol
N (verify) (what is: Y/N?) Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)
Infobox references

Metahexamide (INN) is an anti-diabetic drug from the group of sulfonylureas. It was first described in 1959.^[1]

References

1. ^ Moss JM, Delawter D (September 1959). "Metahexamide in diabetes therapy". Ann NY Acad Sci 82 (2): 614–7. doi:10.1111/j.1749-6632.1959.tb44940.x. PMID 14424617. 

v t e Oral anti-diabetic drugs and Insulin analogs (A10) Insulin Sensitizers Biguanides Metformin# Buformin‡ Phenformin‡ TZDs (PPAR) Pioglitazone Rivoglitazone† Rosiglitazone Troglitazone‡ Dual PPAR agonist Aleglitazar† Muraglitazar§ Tesaglitazar§ Secretagogues K+ ATP Sulfonylureas 1st generation: Acetohexamide Carbutamide Chlorpropamide Metahexamide Tolbutamide Tolazamide 2nd generation: Glibenclamide (Glyburide)# Glibornuride Glipizide Gliquidone Glisoxepide Glyclopyramide Glimepiride Gliclazide Meglitinides/"glinides" Nateglinide Repaglinide Mitiglinide GLP-1 analogs Exenatide Liraglutide Taspoglutide† Albiglutide† Lixisenatide DPP-4 inhibitors Alogliptin† Gemigliptin† Linagliptin Saxagliptin Sitagliptin Vildagliptin Analogs/other insulins fast-acting (Insulin lispro Insulin aspart Insulin glulisine) short-acting (Regular insulin) long-acting (Insulin glargine Insulin detemir NPH insulin) ultra-long-acting (Insulin degludec†) inhalable Exubera‡ Other Alpha-glucosidase inhibitors Acarbose Miglitol Voglibose Amylin analog Pramlintide SGLT2 inhibitors Canagliflozin† Dapagliflozin† Remogliflozin§ Sergliflozin§ Other Benfluorex‡ Tolrestat‡ #WHO-EM ‡Withdrawn from market Clinical trials: †Phase III §Never to phase III M: END anat/phys/devp/horm noco(d)/cong/tumr, sysi/epon proc, drug (A10/H1/H2/H3/H5)

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