metal response element binding protein
Oxford Dictionary of Biochemistry:
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metal response element binding protein
abbr.: MREBP; a mammalian protein that activates basal and heavy metal-induced transcription of metallothionein genes by binding to the metal response element in their promoter regions. MREBP1 contains a DNA-binding region of six C2H2 zinc fingers and three functional activation domains. Knockout of the mouse gene results in death of embryos with variable degrees of liver damage.
| metal response element, metal proteinase, metal | |
| metal-chelate affinity chromatography, metal-ion buffer, metallo+ |
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Oxford Dictionary of Biochemistry
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