Methemoglobin reductase

Ribbon diagram of erythrocytic methemoglobin reductase with FAD bound. From PDB 1UMK.
cytochrome b5 reductase 3
Identifiers
Symbol	CYB5R3
Alt. Symbols	DIA1
Entrez	1727
HUGO	2873
OMIM	250800
PDB	1UMK
RefSeq	NM_007326
UniProt	P00387
Other data
EC number	1.6.2.2
Locus	Chr. 22 q13.31-qter

Methemoglobin reductase (also known as cytochrome-b₅ reductase) is a NADH-dependent enzyme that converts methemoglobin to hemoglobin.

See also

• Methemoglobinemia
• Reductase

External links

• MeSH Methemoglobin+reductase

v • d • e Oxidoreductases: NADH or NADPH (EC 1.6) 1.6.1: NAD/NADP NAD(P)+ transhydrogenase (B-specific) 1.6.2: Heme Methemoglobin reductase · NADPH-hemoprotein reductase/Cytochrome P450 reductase · NADPH-cytochrome-c2 reductase · Leghemoglobin reductase 1.6.3: Oxygen NADPH oxidase (P91-PHOX, Neutrophil cytosolic factor 1, Neutrophil cytosolic factor 2, Neutrophil cytosolic factor 4) · dual oxidase (Dual oxidase 1, Dual oxidase 2) 1.6.5: Quinone or similar NADH dehydrogenase 1.6.6: Nitrogenous group Trimethylamine-N-oxide reductase 1.6.99: other NADH dehydrogenase (quinone)

v • d • e Protein: flavoproteins Acetolactate synthase - Acyl CoA dehydrogenase - Apoptosis-inducing factor - Butyryl CoA dehydrogenase - Cryptochrome - Cytochrome b5 reductase - Dihydrolipoamide dehydrogenase - Flavodoxin - Methemoglobin reductase - Methylenetetrahydrofolate reductase - NADH dehydrogenase - NADPH oxidase - Nitrate reductase - Sarcosine oxidase - Thioredoxin reductase

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