Methisazone
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Methisazone
| Methisazone | |
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[(1-Methyl-2-oxoindol-3-ylidene)amino]thiourea |
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Other names
Metisazone |
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| Identifiers | |
| CAS number | 1910-68-5  |
| PubChem | 6861563 |
| UNII | K3QML4J07E  |
| ChEMBL | CHEMBL1512080 |
| Jmol-3D images | Image 1 |
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| Properties | |
| Molecular formula | C10H10N4OS |
| Molar mass | 234.28 g/mol |
 (verify) (what is:  / ?)Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa) |
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| Infobox references | |
Methisazone is an antiviral drug that works by inhibiting mRNA and protein synthesis, especially in pox viruses. It has been used in the past to treat smallpox.[1]
Methisazone has been described as being used in prophylaxis since at least 1965.[2][3]
References
- ^ Methisazone, Merriam-Webster's Medical Dictionary
- ^ do Valle, LA; de Melo, PR; de Gomes, LF; Proença, LM (13 Nov 1965). "Methisazone in prevention of variola minor among contacts". Lancet 2 (7420): 976–8. PMID 4159212.
- ^ Weiss MM, Weiss PD, Mathisen G, Guze P (December 2004). "Rethinking smallpox". Clin. Infect. Dis. 39 (11): 1668–73. doi:10.1086/425745. PMID 15578369. http://www.journals.uchicago.edu/cgi-bin/resolve?CID34015.
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