methylated-DNA-protein-cysteine S-methyltransferase
Oxford Dictionary of Biochemistry:
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methylated-DNA-protein-cysteine S-methyltransferase
EC 2.1.1.63; other names: 6-O-methylguanine-DNA methyltransferase; O6-methylguanine-DNA-alkyltransferase. It catalyses the reaction between DNA (containing 6-O-methylguanine) and protein l-cysteine to form DNA (without 6-O-methylguanine) and protein S-methyl-l-cysteine. As the acceptor is in the enzyme itself this is a 'suicidal' reaction. Bacterial and mammalian enzymes have common motifs.
| methylate, methylaspartate mutase, methylaspartate ammonia-lyase | |
| methylation of DNA, methylcrotonyl-CoA carboxylase, methyldopa |
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Oxford Dictionary of Biochemistry
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