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People who have had a prior unusual or allergic reaction to either minoxidil or propylene glycol, a nonactive chemical in the Rogaine solution, should not use topical minoxidil. People who have had a previous allergic reaction to preservatives or dyes may also be at risk for having an allergic reaction to minoxidil.
People who are using cortisone, or cortisone-like drugs (corticosteroids), petroleum jelly (Vaseline), or tretinoin (Retin-A) on their scalps should consult their doctors prior to using minoxidil. The use of any of these products in conjunction with minoxidil may cause excessive minoxidil absorption into the body and increase the risk of side effects.
Also, people who have skin problems or irritations of the scalp, including sunburn, may absorb too much minoxidil and increase their risk of side effects.
As for oral minoxidil, the form prescribed for high blood pressure, patients should use minoxidil only under medical supervision to ensure that excessive amounts of the drug are not absorbed into their bodies. Large amounts of minoxidil may increase the severity of the symptoms and side effects of hypertension.
Minoxidil may pass from mother to child through breast milk. Therefore, women who are breastfeeding should not use minoxidil.
— Paul A. Johnson
