Mitiglinide
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Mitiglinide
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| Systematic (IUPAC) name | |
| (2S)-2-benzyl-4-[(3aR,7aS)-octahydro-2H-isoindol- 2-yl]-4-oxobutanoic acid | |
| Clinical data | |
| AHFS/Drugs.com | International Drug Names |
| Pregnancy cat. | ? |
| Legal status | ? |
| Routes | oral |
| Identifiers | |
| CAS number | 207844-01-7  |
| ATC code | A10BX08 |
| PubChem | CID 121891 |
| DrugBank | DB01252 |
| ChemSpider | 108739  |
| UNII | D86I0XLB13 |
| KEGG | D01854 |
| ChEMBL | CHEMBL471498 |
| Chemical data | |
| Formula | C19H25NO3 |
| Mol. mass | 315.41 g/mol |
| SMILES | eMolecules & PubChem |
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Mitiglinide (INN, trade name Glufast) is a drug for the treatment of type 2 diabetes.[1]
Mitiglinide belongs to the meglitinide class of blood glucose-lowering drugs and is currently co-marketed in Japan by Kissei and Takeda. The North America rights to mitiglinide are held by Elixir Pharmaceuticals. Mitiglinide has not yet gained FDA approval.
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Contents
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Pharmacology
Mitiglinide is thought to stimulate insulin secretion by closing the ATP-sensitive K(+) K(ATP) channels in pancreatic beta-cells.
Dosage
Mitiglinide is delivered in tablet form.
References
- ^ Malaisse WJ (October 2008). "Mitiglinide: a rapid- and short-acting non-sulfonylurea insulinotropic agent for the treatment of type 2 diabetic patients". Expert Opin Pharmacother 9 (15): 2691–8. doi:10.1517/14656566.9.15.2691. PMID 18803455. http://www.informapharmascience.com/doi/abs/10.1517/14656566.9.15.2691.
External links
- Elixir Pharmaceuticals - website of the U.S. rights holder for mitiglinide.
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