Monokine

A cytokine produced by macrophages that act on T lymphocytes to enhance cell-mediated immunity, e.g. interleukin 1.

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A monokine is a type of cytokine produced primarily by monocytes and macrophages.

Examples include interleukin 1 and tumor necrosis factor-alpha.

Functions

Monokines released from macrophages can attract Neutrophils , via the process chemotaxis.

See also

• Lymphokine

External links

• MeSH Monokines

• Monokine at eMedicine Dictionary

v • d • e Cell signaling: cytokines By family Interleukin IL-1 superfamily 1 (1Ra) · 18 · 33 IL-6 like/gp130 using 6  · 11 · 27 · 30 · 31 (+non IL Oncostatin M, Leukemia inhibitory factor, Ciliary neurotrophic factor, Cardiotrophin 1) IL-10 family 10 · 19 · 20 · 22 · 24 · 26 Interferon type III 28 · 29 Common γ-chain family 2/15 · 3 · 4 · 7 · 9 · 13 · 21 IL-12 family 12 · 23 · 27 · 35 Other 5 · 8 · 14 · 16 · 17/25 (A) · 32 Chemokine CCL 1 · 2 · 3 · 4 · 5 · 6 · 7 · 8 · 9 · 10 · 11 · 12 · 13 · 14 · 15 · 16 · 17 · 18 · 19 · 20 · 21 · 22 · 23 · 24 · 25 · 26 · 27 · 28 CXCL 1 · 2 · 3 · 4 · 5 · 6 · 7 · 8 · 9 · 10 · 11 · 12 · 13 · 14 · 15 · 16 · 17 CX3CL 1 XCL 1 · 2 TNF Main TNF-alpha TNF (ligand) superfamily 4-1BB ligand · B-cell activating factor · FAS ligand · Lymphotoxin · OX40L · RANKL · TRAIL Cluster of differentiation CD70 · CD153 · CD154 Interferon I alpha (Pegylated 2a, Pegylated 2b), beta (1a, 1b) II Gamma III 28 · 29 Other Monokine · Lymphokine (Lymphotoxin, Transfer factor) · Growth factor · Hematopoietic (Stem cell factor, Colony-stimulating factor) · Autocrine motility factor · Osteopontin By function proinflammatory cytokine (IL-1, TNF-alpha) · Th1 (interferon-gamma and tumor necrosis factor-beta) Th2 (interleukin 4, interleukin 5, interleukin 6, interleukin 10, interleukin 13)

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