Morpheridine
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Morpheridine
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| Systematic (IUPAC) name | |
| ethyl 1-(2-morpholin-4-ylethyl)-4-phenyl-piperidine-4-carboxylate | |
| Clinical data | |
| Pregnancy cat. | ? |
| Legal status | CD (UK) Schedule I (US) international schedule I |
| Identifiers | |
| CAS number | 469-81-8  |
| ATC code | None |
| PubChem | CID 61121 |
| ChemSpider | 55069 |
| UNII | 1854GKB41Y |
| Chemical data | |
| Formula | C20H30N2O3 |
| Mol. mass | 346.46 g/mol |
| SMILES | eMolecules & PubChem |
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Morpheridine (Morpholinoethylnorpethidine)[1] is a 4-phenylpiperidine derivative that is related to the opioid analgesic drug pethidine (meperidine). It is a strong analgesic with around 4 times the potency of pethidine,[2] and unlike pethidine, does not cause convulsions, although it produces the standard opioid side effects such as sedation and respiratory depression.[3]
Morpheridine is not currently used in medicine and is a Schedule I drug which is controlled under UN drug conventions.[4]
References
- ^ US 2795581, STERN EDWARD S; ANDERSON RONALD J, "Piperidine Compounds and Their Production", issued 06/11/1957, assigned to J.F. McFarlan & Co
- ^ Holmes, J. M. (1958). "Morpholinoethylnorpethidine hydrochloride in obstetrics". The Journal of obstetrics and gynaecology of the British Empire 65 (1): 98–99. PMID 13514558.
- ^ Green, A. F.; Ward, N. B. (1956). "Analgesic and other properties of morpholinoethylnorpethidine". British journal of pharmacology and chemotherapy 11 (1): 32–34. PMC 1509567. PMID 13304251. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=1509567.
- ^ "Single convention on drugs 1961". http://www.ukcia.org/pollaw/lawlibrary/singleconventiononnarcoticdrugs1961.php.
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