Morphinone

Morphinone
IUPAC name (5α)-3-hydroxy- 17-methyl- 7,8-didehydro- 4,5-epoxy- morphinan- 6-one
Identifiers
CAS number	467-02-7 N
PubChem	5459823
ChemSpider	4573586 Y
UNII	28MBK63MAW Y
ChEBI	CHEBI:16315 Y
ChEMBL	CHEMBL255467 Y
Jmol-3D images	Image 1
SMILES O=C1\C=C/[C@H]5[C@@H]4N(CC[C@@]52c3c(O[C@@H]12)c(O)ccc3C4)C
InChI InChI=1S/C17H17NO3/c1-18-7-6-17-10-3-5-13(20)16(17)21-15-12(19)4-2-9(14(15)17)8-11(10)18/h2-5,10-11,16,19H,6-8H2,1H3/t10-,11+,16-,17-/m0/s1 Y Key: PFBSOANQDDTNGJ-YNHQPCIGSA-N Y InChI=1/C17H17NO3/c1-18-7-6-17-10-3-5-13(20)16(17)21-15-12(19)4-2-9(14(15)17)8-11(10)18/h2-5,10-11,16,19H,6-8H2,1H3/t10-,11+,16-,17-/m0/s1 Key: PFBSOANQDDTNGJ-YNHQPCIGBO
Properties
Molecular formula	C17H17NO3
Molar mass	283.32 g mol−1
N (verify) (what is: Y/N?) Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)
Infobox references

Morphinone is itself not a very potent opioid but it is the intermediate when morphine is being converted to hydromorphone (trade name Dilaudid) which is 4-6 times as potent as morphine.^{[citation needed]}

Chemical structure

Morphinone can be also described as the ketone of morphine: morphin-6-on.

Legal status

Morphinone itself is an active opiate although its potency is closer to codeine than morphine. It is, however, an important precursor and would fall under the purview of the Controlled Substances Act within the United States. Its legal status in other countries varies.

References

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