Myelin-associated glycoprotein
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Myelin-associated glycoprotein
| Myelin associated glycoprotein | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||||||
| Symbols | MAG; GMA; S-MAG; SIGLEC-4A; SIGLEC4A | ||||||||||||
| External IDs | OMIM: 159460 HomoloGene: 1771 GeneCards: MAG Gene | ||||||||||||
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| Orthologs | |||||||||||||
| Species | Human | Mouse | |||||||||||
| Entrez | 4099 | 17136 | |||||||||||
| Ensembl | ENSG00000105695 | ENSMUSG00000036634 | |||||||||||
| UniProt | P20916 | P20917 | |||||||||||
| RefSeq (mRNA) | n/a | NM_010758.2 | |||||||||||
| RefSeq (protein) | n/a | NP_034888.1 | |||||||||||
| Location (UCSC) | Chr 19: 35.78 – 35.8 Mb |
Chr 7: 31.68 – 31.7 Mb |
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| PubMed search | [1] | [2] | |||||||||||
| Identifiers | |
|---|---|
| Symbol | MAG |
| Alt. symbols | GMA |
| Entrez | 4099 |
| HUGO | 6783 |
| OMIM | 159460 |
| RefSeq | NM_080600 |
| UniProt | P20916 |
| Other data | |
| Locus | Chr. 19 q13.1 |
Myelin-associated glycoprotein (MAG, Siglec-4) is a cell membrane glycoprotein that is a member of the SIGLEC family of proteins and is a functional ligand of the NOGO-66 receptor, NgR.[1] MAG is believed to be involved in myelination during nerve regeneration.[2]
See also
External links
References
- ^ Quarles RH (2007). "Myelin-associated glycoprotein (MAG): past, present and beyond". Journal of Neurochemistry 100 (6): 1431–48. doi:10.1111/j.1471-4159.2006.04319.x. PMID 17241126.
- ^ Barton D, Arquint M, Roder J, Dunn R, Francke U (1987). "The myelin-associated glycoprotein gene: mapping to human chromosome 19 and mouse chromosome 7 and expression in quivering mice". Genomics 1 (2): 107–12. doi:10.1016/0888-7543(87)90002-4. PMID 2447011.
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