myelodysplasia

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(′mī·ə·lō·dis′plā·zhə)

(medicine) Abnormal spinal cord development, especially the lumbosacral portion.


('ə-lō-dĭs-plā'zhə, -zhē-ə)
n.

Abnormal development of the spinal cord.

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1. defective development of the spinal cord.
2. disorders of myeloid cells of the bone marrow, either in number or degree of maturity.

  • hemopoietic m. — includes myeloid metaplasia and myelofibrosis, refractory anemia with excess blast cells, and myelomonocytic leukemia.
  • m. syndrome — qualitative defect in stem cells characterized by dysplastic hematopoietic cells and the presence of abnormal blast cells in the blood. There is also anemia, leukopenia and sometimes thrombocytopenia. See also myeloproliferative disease.

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