MYO10
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Myosin X, also known as MYO10, is a protein which in humans is encoded by the MYO10 gene.[1][2][3]
Myosin X is an actin-based motor protein known to associate at the tips of filopodia.[4]
References
- ^ "Entrez Gene: MYO10 myosin X". http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=4651.
- ^ Bement WM, Hasson T, Wirth JA, Cheney RE, Mooseker MS (July 1994). "Identification and overlapping expression of multiple unconventional myosin genes in vertebrate cell types". Proceedings of the National Academy of Sciences of the United States of America 91 (14): 6549–53. doi:10.1073/pnas.91.14.6549. PMC 44240. PMID 8022818. http://www.pnas.org/cgi/pmidlookup?view=long&pmid=8022818.
- ^ Hasson T, Skowron JF, Gilbert DJ, Avraham KB, Perry WL, Bement WM, Anderson BL, Sherr EH, Chen ZY, Greene LA, Ward DC, Corey DP, Mooseker MS, Copeland NG, Jenkins NA (September 1996). "Mapping of unconventional myosins in mouse and human". Genomics 36 (3): 431–9. doi:10.1006/geno.1996.0488. PMID 8884266.
- ^ Berg JS, Cheney RE (March 2002). "Myosin-X is an unconventional myosin that undergoes intrafilopodial motility". Nature Cell Biology 4 (3): 246–50. doi:10.1038/ncb762. PMID 11854753.
Further reading
- Hasson T, Skowron JF, Gilbert DJ, et al. (1997). "Mapping of unconventional myosins in mouse and human.". Genomics 36 (3): 431–9. doi:10.1006/geno.1996.0488. PMID 8884266.
- Nagase T, Ishikawa K, Suyama M, et al. (1999). "Prediction of the coding sequences of unidentified human genes. XI. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.". DNA Res. 5 (5): 277–86. doi:10.1093/dnares/5.5.277. PMID 9872452.
- Rojas K, Serrano de la Peña L, Gallardo T, et al. (2000). "Physical map and characterization of transcripts in the candidate interval for familial chondrocalcinosis at chromosome 5p15.1.". Genomics 62 (2): 177–83. doi:10.1006/geno.1999.5997. PMID 10610710.
- Berg JS, Derfler BH, Pennisi CM, et al. (2000). "Myosin-X, a novel myosin with pleckstrin homology domains, associates with regions of dynamic actin.". J. Cell. Sci.. 113 Pt 19: 3439–51. PMID 10984435.
- Rogers MS, Strehler EE (2001). "The tumor-sensitive calmodulin-like protein is a specific light chain of human unconventional myosin X.". J. Biol. Chem. 276 (15): 12182–9. doi:10.1074/jbc.M010056200. PMID 11278607.
- Cox D, Berg JS, Cammer M, et al. (2002). "Myosin X is a downstream effector of PI(3)K during phagocytosis.". Nat. Cell Biol. 4 (7): 469–77. doi:10.1038/ncb805. PMID 12055636.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932. //www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=139241.
- Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
- Navarro-Lérida I, Martínez Moreno M, Roncal F, et al. (2004). "Proteomic identification of brain proteins that interact with dynein light chain LC8.". Proteomics 4 (2): 339–46. doi:10.1002/pmic.200300528. PMID 14760703.
- Zhang H, Berg JS, Li Z, et al. (2004). "Myosin-X provides a motor-based link between integrins and the cytoskeleton.". Nat. Cell Biol. 6 (6): 523–31. doi:10.1038/ncb1136. PMID 15156152.
- Tokuo H, Ikebe M (2004). "Myosin X transports Mena/VASP to the tip of filopodia.". Biochem. Biophys. Res. Commun. 319 (1): 214–20. doi:10.1016/j.bbrc.2004.04.167. PMID 15158464.
- Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes.". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC 1356129. PMID 16344560. //www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=1356129.
- Sousa AD, Berg JS, Robertson BW, et al. (2006). "Myo10 in brain: developmental regulation, identification of a headless isoform and dynamics in neurons.". J. Cell. Sci. 119 (Pt 1): 184–94. doi:10.1242/jcs.02726. PMID 16371656.
- Bohil AB, Robertson BW, Cheney RE (2006). "Myosin-X is a molecular motor that functions in filopodia formation.". Proc. Natl. Acad. Sci. U.S.A. 103 (33): 12411–6. doi:10.1073/pnas.0602443103. PMC 1567893. PMID 16894163. //www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=1567893.
- Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.". Cell 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983.
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