Myxedema coma

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Myxedema coma
Classification and external resources
ICD-10 E03.5

Myxedema coma is a state of decompensated hypothyroidism. The patient may have lab values identical to a "normal" hypothyroid state, but a stressful event (infections, MI, CVA, drugs, etc.) precipitates the myxedema coma state. Primary symptoms of myxedema coma are altered mental status and hypothermia. Hypoglycemia, hypotension, hyponatremia, bradycardia, and hypoventilation may also occur.[1] Myxedema, although included in the name, is not necessarily seen in myxedema coma.[2]

Treatment

Mechanical ventilation if there is significant hypoxia.

Intravenous high doses of T4, T4 and T3, or T3. IV Levothyroxine (500-800 mcg).

Determine initial cortisol level, and administer corticosteroids (hydrocortisone at 5-10 mg/hr).

Gradual warming with blankets; an external heating source should not be used.

.[3]

References

  1. ^ "Myxedema Coma." UpToDate Online 15.2.
  2. ^ stepup to medicine
  3. ^ Myxedema coma / crisis http://emedicine.medscape.com/article/123577

External links



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