N-Ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline
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N-Ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline
| N-Ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline[1] | |
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2-Ethoxy-2H-quinoline-1-carboxylic acid ethyl ester |
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Other names
Ethyl 1,2-dihydro-2-ethoxyquinoline-1-carboxylate |
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| Identifiers | |
| Abbreviations | EEDQ |
| CAS number | 16357-59-8 |
| PubChem | 27833 |
| Jmol-3D images | Image 1 |
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| Properties | |
| Molecular formula | C14H17NO3 |
| Molar mass | 247.29 g/mol |
| Melting point |
62-67 °C |
 (verify) (what is:  / ?)Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa) |
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| Infobox references | |
N-Ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline (EEDQ) is an irreversible dopamine-receptor antagonist.[2]
EEDQ is also a highly specific reagent for carboxyl groups. It enables the coupling of acylamino acids with amino acid esters in high yield and without racemization.[3]
References
- ^ 2-Ethoxy-1-ethoxycarbonyl-1,2-dihydroquinoline at Sigma-Aldrich
- ^ Neuroscience Letters 1992, 137(2), p.265
- ^ https://www.bachem.com/bachem/bachem/joust/index.cfm?idland=223
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